Analysis of the TGFβ-induced program in primary airway epithelial cells shows essential role of NF-κB/RelA signaling network in type II epithelial mesenchymal transition

BACKGROUND: The airway epithelial cell plays a central role in coordinating the pulmonary response to injury and inflammation. Here, transforming growth factor-β (TGFβ) activates gene expression programs to induce stem cell-like properties, inhibit expression of differentiated epithelial adhesion pr...

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Udgivet i:BMC Genomics
Main Authors: Tian, Bing, Li, Xueling, Kalita, Mridul, Widen, Steven G., Yang, Jun, Bhavnani, Suresh K., Dang, Bryant, Kudlicki, Andrzej, Sinha, Mala, Kong, Fanping, Wood, Thomas G., Luxon, Bruce A., Brasier, Allan R.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506436/
https://ncbi.nlm.nih.gov/pubmed/26187636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1707-x
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