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Varenicline Interactions at the 5-HT(3) Receptor Ligand Binding Site are Revealed by 5-HTBP
[Image: see text] Cys-loop receptors are the site of action of many therapeutic drugs. One of these is the smoking cessation agent varenicline, which has its major therapeutic effects at nicotinic acetylcholine (nACh) receptors but also acts at 5-HT(3) receptors. Here, we report the X-ray crystal st...
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| Udgivet i: | ACS Chem Neurosci |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2015
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505686/ https://ncbi.nlm.nih.gov/pubmed/25648658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500369h |
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