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Tuberous Sclerosis Complex Protein 2-Independent Activation of mTORC1 by Human Cytomegalovirus pUL38

The mammalian target of rapamycin complex 1 (mTORC1) controls cell growth and anabolic metabolism and is a critical host factor activated by human cytomegalovirus (HCMV) for successful infection. The multifunctional HCMV protein pUL38 previously has been reported to activate mTORC1 by binding to and...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Bai, Yadan, Xuan, Baoqin, Liu, Haiyan, Zhong, Jin, Yu, Dong, Qian, Zhikang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505643/
https://ncbi.nlm.nih.gov/pubmed/25972538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01027-15
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