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Human Cytomegalovirus Protein pUL38 Induces ATF4 Expression, Inhibits Persistent JNK Phosphorylation, and Suppresses Endoplasmic Reticulum Stress-Induced Cell Death

The endoplasmic reticulum (ER) is a key organelle involved in sensing and responding to stressful conditions, including those resulting from infection of viruses, such as human cytomegalovirus (HCMV). Three signaling pathways collectively termed the unfolded protein response (UPR) are activated to r...

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Detalhes bibliográficos
Main Authors: Xuan, Baoqin, Qian, Zhikang, Torigoi, Emi, Yu, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663240/
https://ncbi.nlm.nih.gov/pubmed/19193809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02307-08
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