Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs)

The endosomal sorting complexes required for transport (ESCRT) pathway drives reverse topology membrane fission events within multiple cellular pathways, including cytokinesis, multivesicular body biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding. The AAA...

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Vydáno v:J Biol Chem
Hlavní autoři: Han, Han, Monroe, Nicole, Votteler, Jörg, Shakya, Binita, Sundquist, Wesley I., Hill, Christopher P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505595/
https://ncbi.nlm.nih.gov/pubmed/25833946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642355
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