Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs)

The endosomal sorting complexes required for transport (ESCRT) pathway drives reverse topology membrane fission events within multiple cellular pathways, including cytokinesis, multivesicular body biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding. The AAA...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Han, Han, Monroe, Nicole, Votteler, Jörg, Shakya, Binita, Sundquist, Wesley I., Hill, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505595/
https://ncbi.nlm.nih.gov/pubmed/25833946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642355
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