The N-terminal Set-β Protein Isoform Induces Neuronal Death

Set-β protein plays different roles in neurons, but the diversity of Set-β neuronal isoforms and their functions have not been characterized. The expression and subcellular localization of Set-β are altered in Alzheimer disease, cleavage of Set-β leads to neuronal death after stroke, and the full-le...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Trakhtenberg, Ephraim F., Morkin, Melina I., Patel, Karan H., Fernandez, Stephanie G., Sang, Alan, Shaw, Peter, Liu, Xiongfei, Wang, Yan, Mlacker, Gregory M., Gao, Han, Velmeshev, Dmitry, Dombrowski, Susan M., Vitek, Michael P., Goldberg, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505589/
https://ncbi.nlm.nih.gov/pubmed/25833944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.633883
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