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NFAT2 Isoforms Differentially Regulate Gene Expression, Cell Death, and Transformation through Alternative N-Terminal Domains

The NFAT (nuclear factor of activated T cells) family of transcription factors is composed of four calcium-responsive proteins (NFAT1 to -4). The NFAT2 (also called NFATc1) gene encodes the isoforms NFAT2α and NFAT2β that result mainly from alternative initiation exons that provide two different N-t...

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Publicado en:Mol Cell Biol
Autores principales: Lucena, Pedro I., Faget, Douglas V., Pachulec, Emilia, Robaina, Marcela C., Klumb, Claudete E., Robbs, Bruno K., Viola, João P. B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702591/
https://ncbi.nlm.nih.gov/pubmed/26483414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00501-15
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