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Regulating Set-β's Subcellular Localization Toggles Its Function between Inhibiting and Promoting Axon Growth and Regeneration

The failure of the CNS neurons to regenerate axons after injury or stroke is a major clinical problem. Transcriptional regulators like Set-β are well positioned to regulate intrinsic axon regeneration capacity, which declines developmentally in maturing CNS neurons. Set-β also functions at cellular...

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Detalhes bibliográficos
Main Authors: Trakhtenberg, Ephraim F., Wang, Yan, Morkin, Melina I., Fernandez, Stephanie G., Mlacker, Gregory M., Shechter, Jesse M., Liu, Xiongfei, Patel, Karan H., Lapins, Allison, Yang, Steven, Dombrowski, Susan M., Goldberg, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028506/
https://ncbi.nlm.nih.gov/pubmed/24849368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3658-13.2014
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