Two Isoforms of the RNA Binding Protein, Coding Region Determinant-binding Protein (CRD-BP/IGF2BP1), Are Expressed in Breast Epithelium and Support Clonogenic Growth of Breast Tumor Cells

CRD-BP/IGF2BP1 has been characterized as an “oncofetal” RNA binding protein typically highly expressed in embryonic tissues, suppressed in normal adult tissues, but induced in many tumor types. In this study, we show that adult breast tissues express ubiquitous but low levels of CRD-BP protein and m...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Fakhraldeen, Saja A., Clark, Rod J., Roopra, Avtar, Chin, Emily N., Huang, Wei, Castorino, John, Wisinski, Kari B., Kim, TaeWon, Spiegelman, Vladimir S., Alexander, Caroline M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505587/
https://ncbi.nlm.nih.gov/pubmed/25861986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.655175
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi