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Involvement of the mRNA binding protein CRD-BP in the regulation of metastatic melanoma cell proliferation and invasion by hypoxia

We have previously shown that the mRNA binding protein CRD-BP is overexpressed in human melanomas, where it promotes cell survival and resistance to chemotherapy. The present study investigates the role of hypoxia, a common characteristic of the tumor microenvironment, in the regulation of CRD-BP ex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Craig, Evisabel A., Weber, Jonathan D., Spiegelman, Vladimir S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585514/
https://ncbi.nlm.nih.gov/pubmed/23038779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.115204
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