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CRD-BP protects the coding region of βTrCP1 mRNA from miR-183-mediated degradation
miRNAs are largely known to base-pair with the 3′UTR of target mRNAs, downregulating their stability and translation. mRNA of βTrCP1 ubiquitin ligase is very unstable, but unlike the majority of mRNAs where 3′UTR determines the rate of mRNA turnover, βTrCP1 mRNA contains cis-acting destabilizing ele...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742352/ https://ncbi.nlm.nih.gov/pubmed/19647520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.007 |
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