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Inhibition of CRD-BP sensitizes melanoma cells to chemotherapeutic agents

We previously reported that malignant melanomas express high levels of the mRNA binding protein CRD-BP. This molecule is important for the activation of anti-apoptotic pathways, a mechanism often linked to insensitivity to therapeutics. However, it is not known whether CRD-BP plays a role in the res...

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Autori principali: Craig, Evisabel A., Spiegelman, Vladimir S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242936/
https://ncbi.nlm.nih.gov/pubmed/21981993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2011.00921.x
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