The Evolutionarily Conserved C-terminal Domains in the Mammalian Retinoblastoma Tumor Suppressor Family Serve as Dual Regulators of Protein Stability and Transcriptional Potency

The retinoblastoma (RB) tumor suppressor and related family of proteins play critical roles in development through their regulation of genes involved in cell fate. Multiple regulatory pathways impact RB function, including the ubiquitin-proteasome system with deregulated RB destruction frequently as...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Sengupta, Satyaki, Lingnurkar, Raj, Carey, Timothy S., Pomaville, Monica, Kar, Parimal, Feig, Michael, Wilson, Catherine A., Knott, Jason G., Arnosti, David N., Henry, R. William
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505513/
https://ncbi.nlm.nih.gov/pubmed/25903125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599993
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker