The Evolutionarily Conserved C-terminal Domains in the Mammalian Retinoblastoma Tumor Suppressor Family Serve as Dual Regulators of Protein Stability and Transcriptional Potency

The retinoblastoma (RB) tumor suppressor and related family of proteins play critical roles in development through their regulation of genes involved in cell fate. Multiple regulatory pathways impact RB function, including the ubiquitin-proteasome system with deregulated RB destruction frequently as...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sengupta, Satyaki, Lingnurkar, Raj, Carey, Timothy S., Pomaville, Monica, Kar, Parimal, Feig, Michael, Wilson, Catherine A., Knott, Jason G., Arnosti, David N., Henry, R. William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505513/
https://ncbi.nlm.nih.gov/pubmed/25903125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599993
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados