The Evolutionarily Conserved C-terminal Domains in the Mammalian Retinoblastoma Tumor Suppressor Family Serve as Dual Regulators of Protein Stability and Transcriptional Potency

The retinoblastoma (RB) tumor suppressor and related family of proteins play critical roles in development through their regulation of genes involved in cell fate. Multiple regulatory pathways impact RB function, including the ubiquitin-proteasome system with deregulated RB destruction frequently as...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Sengupta, Satyaki, Lingnurkar, Raj, Carey, Timothy S., Pomaville, Monica, Kar, Parimal, Feig, Michael, Wilson, Catherine A., Knott, Jason G., Arnosti, David N., Henry, R. William
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Gene Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505513/
https://ncbi.nlm.nih.gov/pubmed/25903125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599993
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