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Transcriptional Repressor DAXX Promotes Prostate Cancer Tumorigenicity via Suppression of Autophagy

The DAXX transcriptional repressor was originally associated with apoptotic cell death. However, recent evidence that DAXX represses several tumor suppressor genes, including the DAPK1 and DAPK3 protein kinases, and is up-regulated in many cancers argues that a pro-survival role may predominate in a...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Puto, Lorena A., Brognard, John, Hunter, Tony
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505457/
https://ncbi.nlm.nih.gov/pubmed/25903140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.658765
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