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Transcriptional Repressor DAXX Promotes Prostate Cancer Tumorigenicity via Suppression of Autophagy

The DAXX transcriptional repressor was originally associated with apoptotic cell death. However, recent evidence that DAXX represses several tumor suppressor genes, including the DAPK1 and DAPK3 protein kinases, and is up-regulated in many cancers argues that a pro-survival role may predominate in a...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Puto, Lorena A., Brognard, John, Hunter, Tony
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505457/
https://ncbi.nlm.nih.gov/pubmed/25903140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.658765
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