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Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation

The apoptosis-modulating protein Daxx functions as a transcriptional repressor that binds to and suppresses the activity of nuclear factor-κB member RelB, among other transcription factors. The mechanism by which Daxx represses RelB target genes remains elusive. In this report, we demonstrate that D...

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Autors principals: Puto, Lorena A., Reed, John C.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335332/
https://ncbi.nlm.nih.gov/pubmed/18413714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1632208
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