The Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoprotein

Eitemau Tebyg

• Human P-glycoprotein Contains a Greasy Ball-and-Socket Joint at the Second Transmission Interface
  gan: Loo, Tip W., et al.
  Cyhoeddwyd: (2013)
• Locking Intracellular Helices 2 and 3 Together Inactivates Human P-glycoprotein
  gan: Loo, Tip W., et al.
  Cyhoeddwyd: (2014)
• Identification of the Distance between the Homologous Halves of P-glycoprotein That Triggers the High/Low ATPase Activity Switch
  gan: Loo, Tip W., et al.
  Cyhoeddwyd: (2014)
• Cysteines Introduced into Extracellular Loops 1 and 4 of Human P-Glycoprotein That Are Close Only in the Open Conformation Spontaneously Form a Disulfide Bond That Inhibits Drug Efflux and ATPase Activity
  gan: Loo, Tip W., et al.
  Cyhoeddwyd: (2014)
• Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket
  gan: Loo, Tip W., et al.
  Cyhoeddwyd: (2006)