Locking Intracellular Helices 2 and 3 Together Inactivates Human P-glycoprotein

Lignende værker

• The Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoprotein
  af: Loo, Tip W., et al.
  Udgivet: (2015)
• A Salt Bridge in Intracellular Loop 2 Is Essential for Folding of Human P-Glycoprotein
  af: Loo, Tip W., et al.
  Udgivet: (2013)
• Human P-glycoprotein Contains a Greasy Ball-and-Socket Joint at the Second Transmission Interface
  af: Loo, Tip W., et al.
  Udgivet: (2013)
• Identification of the Distance between the Homologous Halves of P-glycoprotein That Triggers the High/Low ATPase Activity Switch
  af: Loo, Tip W., et al.
  Udgivet: (2014)
• Cysteines Introduced into Extracellular Loops 1 and 4 of Human P-Glycoprotein That Are Close Only in the Open Conformation Spontaneously Form a Disulfide Bond That Inhibits Drug Efflux and ATPase Activity
  af: Loo, Tip W., et al.
  Udgivet: (2014)