The Wnt Inhibitor Sclerostin Is Up-regulated by Mechanical Unloading in Osteocytes in Vitro

Although bone responds to its mechanical environment, the cellular and molecular mechanisms underlying the response of the skeleton to mechanical unloading are not completely understood. Osteocytes are the most abundant but least understood cells in bones and are thought to be responsible for sensin...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Spatz, Jordan M., Wein, Marc N., Gooi, Jonathan H., Qu, Yili, Garr, Jenna L., Liu, Shawn, Barry, Kevin J., Uda, Yuhei, Lai, Forest, Dedic, Christopher, Balcells-Camps, Mercedes, Kronenberg, Henry M., Babij, Philip, Pajevic, Paola Divieti
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505423/
https://ncbi.nlm.nih.gov/pubmed/25953900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628313
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