RWD Domain as an E2 (Ubc9)-Interaction Module

An RWD domain is a well conserved domain found through bioinformatic analysis of the human proteome sequence; however, its function has been unknown. Ubiquitin-like modifications require the catalysis of three enzymes generally known as E1, E2, and E3. We solved the crystal structure of the E2 for t...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Alontaga, Aileen Y., Ambaye, Nigus D., Li, Yi-Jia, Vega, Ramir, Chen, Chih-Hong, Bzymek, Krzysztof P., Williams, John C., Hu, Weidong, Chen, Yuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505409/
https://ncbi.nlm.nih.gov/pubmed/25918163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.644047
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