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Safety and Pharmacokinetics of Solithromycin in Subjects with Hepatic Impairment
Solithromycin, a new macrolide and the first fluoroketolide, is in late-stage clinical development and, like older macrolides, is primarily metabolized and excreted through liver-dependent mechanisms. This study evaluated the safety and pharmacokinetics of solithromycin in patients with chronic live...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505280/ https://ncbi.nlm.nih.gov/pubmed/25870056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04652-14 |
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