Identification of New Natural CphA Metallo-β-Lactamases CphA4 and CphA5 in Aeromonas veronii and Aeromonas hydrophila Isolates from Municipal Sewage in Central Italy

Two new natural CphA metallo-β-lactamases, the CphA4 and CphA5 enzymes, were identified in water samples from municipal sewage in central Italy. Compared to CphA, the CphA4 and CphA5 enzymes showed numerous point mutations. These enzymes have a narrow spectrum of substrates focused on carbapenems on...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Bottoni, Carlo, Marcoccia, Francesca, Compagnoni, Chiara, Colapietro, Martina, Sabatini, Alessia, Celenza, Giuseppe, Segatore, Bernardetta, Maturo, Maria Giovanna, Amicosante, Gianfranco, Perilli, Mariagrazia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505251/
https://ncbi.nlm.nih.gov/pubmed/25987617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00628-15
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