Identification of New Natural CphA Metallo-β-Lactamases CphA4 and CphA5 in Aeromonas veronii and Aeromonas hydrophila Isolates from Municipal Sewage in Central Italy

Two new natural CphA metallo-β-lactamases, the CphA4 and CphA5 enzymes, were identified in water samples from municipal sewage in central Italy. Compared to CphA, the CphA4 and CphA5 enzymes showed numerous point mutations. These enzymes have a narrow spectrum of substrates focused on carbapenems on...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bottoni, Carlo, Marcoccia, Francesca, Compagnoni, Chiara, Colapietro, Martina, Sabatini, Alessia, Celenza, Giuseppe, Segatore, Bernardetta, Maturo, Maria Giovanna, Amicosante, Gianfranco, Perilli, Mariagrazia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505251/
https://ncbi.nlm.nih.gov/pubmed/25987617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00628-15
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