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Competitive Inhibitors of the CphA Metallo-β-Lactamase from Aeromonas hydrophila

Various inhibitors of metallo-β-lactamases have been reported; however, none are effective for all subgroups. Those that have been found to inhibit the enzymes of subclass B2 (catalytically active with one zinc) either contain a thiol (and show less inhibition towards this subgroup than towards the...

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Autors principals: Horsfall, L. E., Garau, G., Liénard, B. M. R., Dideberg, O., Schofield, C. J., Frère, J. M., Galleni, M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891371/
https://ncbi.nlm.nih.gov/pubmed/17307979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00866-06
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