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Effect of Qnr on Plasmid Gyrase Toxins CcdB and ParE

Plasmid toxins CcdB and ParE are part of addiction systems promoting plasmid maintenance. Both target host DNA gyrase, as do quinolones and plasmid-determined Qnr proteins that protect gyrase from quinolone inhibition. We cloned qnrB4, qnrS1, ccdB, parE, and the antitoxin-encoding genes ccdA and par...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Kwak, Yee Gyung, Jacoby, George A., Hooper, David C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505230/
https://ncbi.nlm.nih.gov/pubmed/26055367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00524-15
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