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Effect of Qnr on Plasmid Gyrase Toxins CcdB and ParE

Plasmid toxins CcdB and ParE are part of addiction systems promoting plasmid maintenance. Both target host DNA gyrase, as do quinolones and plasmid-determined Qnr proteins that protect gyrase from quinolone inhibition. We cloned qnrB4, qnrS1, ccdB, parE, and the antitoxin-encoding genes ccdA and par...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Kwak, Yee Gyung, Jacoby, George A., Hooper, David C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505230/
https://ncbi.nlm.nih.gov/pubmed/26055367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00524-15
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