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Driving Forces of Gyrase Recognition by the Addiction Toxin CcdB
Gyrase, an essential bacterial topoisomerase, is the target of several antibiotics (e.g. quinolones) as well as of bacterial toxin CcdB. This toxin, encoded by Escherichia coli toxin-antitoxin module ccd, poisons gyrase by causing inhibition of both transcription and replication. Because the molecul...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740426/ https://ncbi.nlm.nih.gov/pubmed/19465484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014035 |
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