Abraxane, the Nanoparticle Formulation of Paclitaxel Can Induce Drug Resistance by Up-Regulation of P-gp

P-glycoprotein (P-gp) can actively pump paclitaxel (PTX) out of cells and induces drug resistance. Abraxane, a nanoparticle (NP) formulation of PTX, has multiple clinical advantages over the single molecule form. However, it is still unclear whether Abraxane overcomes the common small molecule drug...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhao, Minzhi, Lei, Chunni, Yang, Yadong, Bu, Xiangli, Ma, Huailei, Gong, He, Liu, Juan, Fang, Xiangdong, Hu, Zhiyuan, Fang, Qiaojun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504487/
https://ncbi.nlm.nih.gov/pubmed/26182353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131429
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados