NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel

Paclitaxel (PTX) is one of the most effective anticancer agents. In clinical practice, however, high incidences of adverse reactions of the drug, for example, neurotoxicity, myelosuppression, and allergic reactions, have been reported. NK105, a micellar nanoparticle formulation, was developed to ove...

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Hlavní autoři: Hamaguchi, T, Matsumura, Y, Suzuki, M, Shimizu, K, Goda, R, Nakamura, I, Nakatomi, I, Yokoyama, M, Kataoka, K, Kakizoe, T
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2005
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361981/
https://ncbi.nlm.nih.gov/pubmed/15785749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602479
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