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NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel

Paclitaxel (PTX) is one of the most effective anticancer agents. In clinical practice, however, high incidences of adverse reactions of the drug, for example, neurotoxicity, myelosuppression, and allergic reactions, have been reported. NK105, a micellar nanoparticle formulation, was developed to ove...

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Detalhes bibliográficos
Main Authors: Hamaguchi, T, Matsumura, Y, Suzuki, M, Shimizu, K, Goda, R, Nakamura, I, Nakatomi, I, Yokoyama, M, Kataoka, K, Kakizoe, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361981/
https://ncbi.nlm.nih.gov/pubmed/15785749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602479
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