NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel

Paclitaxel (PTX) is one of the most effective anticancer agents. In clinical practice, however, high incidences of adverse reactions of the drug, for example, neurotoxicity, myelosuppression, and allergic reactions, have been reported. NK105, a micellar nanoparticle formulation, was developed to ove...

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Bibliografski detalji
Glavni autori: Hamaguchi, T, Matsumura, Y, Suzuki, M, Shimizu, K, Goda, R, Nakamura, I, Nakatomi, I, Yokoyama, M, Kataoka, K, Kakizoe, T
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2005
Teme:
Translational Therapeutics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361981/
https://ncbi.nlm.nih.gov/pubmed/15785749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602479
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