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NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel

Paclitaxel (PTX) is one of the most effective anticancer agents. In clinical practice, however, high incidences of adverse reactions of the drug, for example, neurotoxicity, myelosuppression, and allergic reactions, have been reported. NK105, a micellar nanoparticle formulation, was developed to ove...

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Autores principales: Hamaguchi, T, Matsumura, Y, Suzuki, M, Shimizu, K, Goda, R, Nakamura, I, Nakatomi, I, Yokoyama, M, Kataoka, K, Kakizoe, T
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361981/
https://ncbi.nlm.nih.gov/pubmed/15785749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602479
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