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An in vivo mechanism for the reduced peripheral neurotoxicity of NK105: a paclitaxel-incorporating polymeric micellar nanoparticle formulation
In our previous rodent studies, the paclitaxel (PTX)-incorporating polymeric micellar nanoparticle formulation NK105 had showed significantly stronger antitumor effects and reduced peripheral neurotoxicity than PTX dissolved in Cremophor(®) EL and ethanol (PTX/CRE). Thus, to elucidate the mechanisms...
Gorde:
| Argitaratua izan da: | Int J Nanomedicine |
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| Egile Nagusiak: | , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Dove Medical Press
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5317268/ https://ncbi.nlm.nih.gov/pubmed/28243090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S114356 |
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