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Could the Anti-Chaperone VER155008 Replace Temozolomide for Glioma Treatment

Cancer inducible molecular chaperone HSP90 is of great importance as an anticancer target. Proteomic analysis showed that inhibiting HSP90 by the geldanamycin derivative, 17-AAG elevated the expression of the co-chaperone Hsp70. In this study we used HSP90 selective inhibitor 17-AAG and HSP70/90 dua...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Shervington, Leroy, Patil, Harshada, Shervington, Amal
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504115/
https://ncbi.nlm.nih.gov/pubmed/26185541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.12251
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