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Targeting autophagy to sensitive glioma to temozolomide treatment

Temozolomide (TMZ), an alkylating agent, is widely used for treating primary and recurrent high-grade gliomas. However, the efficacy of TMZ is often limited by the development of resistance. Recently, studies have found that TMZ treatment could induce autophagy, which contributes to therapy resistan...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Yan, Yuanliang, Xu, Zhijie, Dai, Shuang, Qian, Long, Sun, Lunquan, Gong, Zhicheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736617/
https://ncbi.nlm.nih.gov/pubmed/26830677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0303-5
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