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Targeting autophagy to sensitive glioma to temozolomide treatment
Temozolomide (TMZ), an alkylating agent, is widely used for treating primary and recurrent high-grade gliomas. However, the efficacy of TMZ is often limited by the development of resistance. Recently, studies have found that TMZ treatment could induce autophagy, which contributes to therapy resistan...
Enregistré dans:
| Publié dans: | J Exp Clin Cancer Res |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4736617/ https://ncbi.nlm.nih.gov/pubmed/26830677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0303-5 |
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