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Targeting autophagy to sensitive glioma to temozolomide treatment
Temozolomide (TMZ), an alkylating agent, is widely used for treating primary and recurrent high-grade gliomas. However, the efficacy of TMZ is often limited by the development of resistance. Recently, studies have found that TMZ treatment could induce autophagy, which contributes to therapy resistan...
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Publicado no: | J Exp Clin Cancer Res |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4736617/ https://ncbi.nlm.nih.gov/pubmed/26830677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0303-5 |
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