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Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling

The transcription factor PLZF (promyelocytic leukemia zinc finger; zbtb16) is essential for nearly all of the unique characteristics of NKT cells including their rapid and potent response to antigen. In the immune system, zbtb16 expression is only found in innate cells. Conventional T cells that ect...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Sai, Laouar, Amale, Denzin, Lisa K., Sant’Angelo, Derek B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503983/
https://ncbi.nlm.nih.gov/pubmed/26178856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12113
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