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Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling

The transcription factor PLZF (promyelocytic leukemia zinc finger; zbtb16) is essential for nearly all of the unique characteristics of NKT cells including their rapid and potent response to antigen. In the immune system, zbtb16 expression is only found in innate cells. Conventional T cells that ect...

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Publicat a:Sci Rep
Autors principals: Zhang, Sai, Laouar, Amale, Denzin, Lisa K., Sant’Angelo, Derek B.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503983/
https://ncbi.nlm.nih.gov/pubmed/26178856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12113
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