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Development of a Fluorescent Quenching Based High Throughput Assay to Screen for Calcineurin Inhibitors

Currently there is no effective treatment available for major neurodegenerative disorders associated to protein misfolding, including Alzheimer’s and Parkinson's disease. One of most promising therapeutic approaches under development focuses on inhibiting the misfolding and aggregation pathway....

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Mukherjee, Abhisek, Syeb, Kathleen, Concannon, John, Callegari, Keri, Soto, Claudio, Glicksman, Marcie A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503349/
https://ncbi.nlm.nih.gov/pubmed/26176772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131297
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