Development of a Fluorescent Quenching Based High Throughput Assay to Screen for Calcineurin Inhibitors

Currently there is no effective treatment available for major neurodegenerative disorders associated to protein misfolding, including Alzheimer’s and Parkinson's disease. One of most promising therapeutic approaches under development focuses on inhibiting the misfolding and aggregation pathway....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Mukherjee, Abhisek, Syeb, Kathleen, Concannon, John, Callegari, Keri, Soto, Claudio, Glicksman, Marcie A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503349/
https://ncbi.nlm.nih.gov/pubmed/26176772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131297
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