Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus

BACKGROUND: Predisposition to childhood otitis media (OM) has a strong genetic component, with polymorphisms in innate immunity genes suspected to contribute to risk. Studies on several genes have been conducted, but most associations have failed to replicate in independent cohorts. METHODS: We inve...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Hafrén, Lena, Einarsdottir, Elisabet, Kentala, Erna, Hammarén-Malmi, Sari, Bhutta, Mahmood F., MacArthur, Carol J., Wilmot, Beth, Casselbrant, Margaretha, Conley, Yvette P., Weeks, Daniel E., Mandel, Ellen M., Vaarala, Outi, Kallio, Anna, Melin, Merit, Nieminen, Janne K., Leinonen, Eira, Kere, Juha, Mattila, Petri S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503307/
https://ncbi.nlm.nih.gov/pubmed/26177520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132551
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