Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus

BACKGROUND: Predisposition to childhood otitis media (OM) has a strong genetic component, with polymorphisms in innate immunity genes suspected to contribute to risk. Studies on several genes have been conducted, but most associations have failed to replicate in independent cohorts. METHODS: We inve...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hafrén, Lena, Einarsdottir, Elisabet, Kentala, Erna, Hammarén-Malmi, Sari, Bhutta, Mahmood F., MacArthur, Carol J., Wilmot, Beth, Casselbrant, Margaretha, Conley, Yvette P., Weeks, Daniel E., Mandel, Ellen M., Vaarala, Outi, Kallio, Anna, Melin, Merit, Nieminen, Janne K., Leinonen, Eira, Kere, Juha, Mattila, Petri S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503307/
https://ncbi.nlm.nih.gov/pubmed/26177520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132551
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