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Mechanistic analysis of solute transport in an in vitro physiological two-phase dissolution apparatus

In vitro dissolution methodologies that adequately capture the oral bioperformance of solid dosage forms are critical tools needed to aid formulation development. Such methodologies must encompass important physiological parameters and be designed with drug properties in mind. Two-phase dissolution...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biopharm Drug Dispos
Hauptverfasser: Mudie, Deanna M., Shi, Yi, Ping, Haili, Gao, Ping, Amidon, Gordon L., Amidon, Gregory E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503256/
https://ncbi.nlm.nih.gov/pubmed/22847296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.1803
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