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Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties

The rate and extent of drug dissolution in the gastrointestinal (GI) tract are highly dependent upon drug physicochemical properties and GI fluid properties. Biorelevant dissolution media (BDM), which aim to facilitate in vitro prediction of in vivo dissolution performance, have evolved with our und...

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Bibliografische gegevens
Gepubliceerd in:AAPS J
Hoofdauteurs: Mudie, Deanna M., Samiei, Nasim, Marshall, Derrick J., Amidon, Gregory E., Bergström, Christel A.S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985051/
https://ncbi.nlm.nih.gov/pubmed/31989343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-020-0417-8
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