Učitavanje...
On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics
TRAIL and agonistic antibodies against TRAIL death receptors kill tumor cells while causing virtually no damage to normal cells. Several novel drugs targeting TRAIL receptors are currently in clinical trials. However, TRAIL resistance is a common obstacle in TRAIL based therapy and limits the effici...
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| Izdano u: | Oncogene |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502956/ https://ncbi.nlm.nih.gov/pubmed/22580613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.164 |
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