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TRAIL Receptor-targeted therapeutics: Resistance mechanisms and strategies to avoid them
Tumor Necrosis factor-Related Apoptosis-Inducing Ligand (TRAIL) receptors are attractive therapeutic targets in cancer because agents that activate these receptors directly induce tumor cell apoptosis and have low toxicity to normal tissues. Consequently, several different drugs that target these re...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435079/ https://ncbi.nlm.nih.gov/pubmed/18374623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2008.02.001 |
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