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V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation

Recently a noncanonical activity of autophagy proteins has been discovered that targets lipidation of microtubule-associated protein 1 light chain 3 (LC3) onto macroendocytic vacuoles, including macropinosomes, phagosomes, and entotic vacuoles. While this pathway is distinct from canonical autophagy...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Florey, Oliver, Gammoh, Noor, Kim, Sung Eun, Jiang, Xuejun, Overholtzer, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502810/
https://ncbi.nlm.nih.gov/pubmed/25484071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.984277
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