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A role for TOR complex 2 signaling in promoting autophagy

The conserved target of rapamycin (TOR) kinase is a central regulator of cell growth in response to nutrient availability. TOR forms 2 structurally and functionally distinct complexes, TORC1 and TORC2, and negatively regulates autophagy via TORC1. Here we demonstrate TOR also operates independently...

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Foilsithe in:Autophagy
Main Authors: Vlahakis, Ariadne, Powers, Ted
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502789/
https://ncbi.nlm.nih.gov/pubmed/25426890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.36262
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