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TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy

The highly conserved Target of Rapamycin (TOR) kinase is a central regulator of cell growth and metabolism in response to nutrient availability. TOR functions in two structurally and functionally distinct complexes, TOR Complex 1 (TORC1) and TOR Complex 2 (TORC2). Through TORC1, TOR negatively regul...

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Détails bibliographiques
Auteurs principaux: Vlahakis, Ariadne, Graef, Martin, Nunnari, Jodi, Powers, Ted
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115538/
https://ncbi.nlm.nih.gov/pubmed/25002487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406305111
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