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TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy
The highly conserved Target of Rapamycin (TOR) kinase is a central regulator of cell growth and metabolism in response to nutrient availability. TOR functions in two structurally and functionally distinct complexes, TOR Complex 1 (TORC1) and TOR Complex 2 (TORC2). Through TORC1, TOR negatively regul...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4115538/ https://ncbi.nlm.nih.gov/pubmed/25002487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406305111 |
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