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A role for TOR complex 2 signaling in promoting autophagy
The conserved target of rapamycin (TOR) kinase is a central regulator of cell growth in response to nutrient availability. TOR forms 2 structurally and functionally distinct complexes, TORC1 and TORC2, and negatively regulates autophagy via TORC1. Here we demonstrate TOR also operates independently...
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| Publicado en: | Autophagy |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502789/ https://ncbi.nlm.nih.gov/pubmed/25426890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.36262 |
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