Periodontal Defects in the A116T Knock-in Murine Model of Odontohypophosphatasia

Mutations in ALPL result in hypophosphatasia (HPP), a disease causing defective skeletal mineralization. ALPL encodes tissue nonspecific alkaline phosphatase (ALP), an enzyme that promotes mineralization by reducing inorganic pyrophosphate, a mineralization inhibitor. In addition to skeletal defects...

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Detalhes bibliográficos
Publicado no:J Dent Res
Main Authors: Foster, B.L., Sheen, C.R., Hatch, N.E., Liu, J., Cory, E., Narisawa, S., Kiffer-Moreira, T., Sah, R.L., Whyte, M.P., Somerman, M.J., Millán, J.L.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502784/
https://ncbi.nlm.nih.gov/pubmed/25716980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034515573273
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