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Periodontal Defects in the A116T Knock-in Murine Model of Odontohypophosphatasia
Mutations in ALPL result in hypophosphatasia (HPP), a disease causing defective skeletal mineralization. ALPL encodes tissue nonspecific alkaline phosphatase (ALP), an enzyme that promotes mineralization by reducing inorganic pyrophosphate, a mineralization inhibitor. In addition to skeletal defects...
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| Pubblicato in: | J Dent Res |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SAGE Publications
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502784/ https://ncbi.nlm.nih.gov/pubmed/25716980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034515573273 |
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